Additionally, hs-CRP (OR, 2.750; 95% CI, 2.028–3.729; P < 0.001), renal dysfunction (OR, 9.582; 95% CI, 3.312–27.725; P < 0.001), diabetes mellitus (OR, 3.089; 95% CI, 1.101–8.668; P = 0.032), ST-elevation myocardial infarction (STEMI) (OR, 3.839; 95% CI, 1.342–10.985; P = 0.012), and cystatin C (OR, 1.099; 95% CI, 1.060–1.140; P < 0.001) were also independent risk factors of CIN. This evidence concerns the gene CST3 and Abnormal renal physiology.