After adjusting for age, history of hypertension and/or diabetes, LVEF < 40%, eGFR < 60 mL/min/1.73 m2, levels of uric acid, cystatin C, hs-CRP, clinical diagnosis of acute myocardial infarction (AMI), and 3-vessel disease, SF was still significantly associated with an increased risk of CIN (OR, 1.008; 95% CI, 1.003–1.013; P = 0.002). This evidence concerns the gene CRP and Hypertension.