For example, phosphorodiamidate morpholino oligonucleotide (PMO)-mediated dystrophin restoration therapy in mdx mice was able to correct the dysregulation of the myomiRs (miR-1, -133a/b, -206) to normal wild type levels in mouse serum indicating the dynamic nature of microRNA expression in neuromuscular disease [34]. Here, DMD is linked to neuromuscular disease.