TNF and bacterial infectious disease: Comparable results regarding such high levels of IL1-β, TNF-α and IFN-γ were detected in pigs with viral respiratory disease (Van Reeth & Nauwynck, 2000) and cattle with bacterial infection (Pace et al., 1993; Horadagoda et al., 1994; Morsey et al., 1999; Kasimanickam et al., 2013; El-Deeb & Elmoslemany, 2016).