By contrast, vWF, a reliable marker of endothelial dysfunction, were not significantly different from population levels, in contrast to Hope (17) of increased vWF in patients with schizophrenia compared to healthy controls (p < 0.05), increased vWF associated with small increase of CRP, and CRP and vWF positively associated with disease severity. The gene discussed is VWF; the disease is endothelial dysfunction.