In breast cancer, the cytokines concerned with the differentiation of MDSCs from bone marrow progenitors include G-CSF [17], M-CSF [18], GM-CSF [19], IL-6 [20], IL-1β [21], macrophage migration inhibitory factor (MIF) [22], TGF-β1 [23]. The gene discussed is CSF3; the disease is breast carcinoma.