Aberrant (mostly high) expression of Kv1.3 has instead been observed in different types of tumors [13, 15], such as melanoma [16], prostate [17], breast [18], B-cell lymphoma [19], chronic lymphocytic leukemia (B-CLL) [20, 21] gastric [22], pancreatic tumor [23] and in lung cancer [24]. This evidence concerns the gene KCNA3 and B-cell chronic lymphocytic leukemia.