CXCL1 and Familial prostate cancer: CXCL1 (chemokine with C-X-C motif ligand 1) is a member of the CXC chemokine family and promotes neoplastic transformation, tumorigenesis, and angiogenesis in breast, lung, pancreatic, colorectal, bladder, and prostate cancer, as well as in melanoma, by binding specifically to CXCR2 [4–9].