By Kaplan-Meier method and log-rank test, high CXCL12 and CXCR7 expressions in tumor tissues predicted poor overall survival in two cohorts (P=0.040 and =0.037 for CXCL12; P=0.007 and =0.020 for CXCR7; Figures 1G, 1H, Supplementary Figures S1G, S1H, Tables 1 and Supplementary Figure S3). Here, ACKR3 is linked to neoplasm.