As shown in Figure 2, the results similarly indicate that DLL4 was down-regulated in invasive ductal carcinoma (Figure 2A), renal carcinoma (Figure 2B), prostate adenocarcinoma (Figure 2C) and lung small cell carcinoma (Figure 2D) all in contrast to their corresponding normal tissues or benign hyperplasia (prostate). The gene discussed is DLL4; the disease is renal carcinoma.