The third immune-related SNP, rs191177147 at 3q28 (P=9.8 × 10−17, OR=1.11, logistic regression), resides within an intron of LPP and is in LD with rs1464510 (r2=0.54) and rs9860547 (r2=0.68, Supplementary Table 17); the former is associated with autoimmune diseases such as celiac disease, rheumatoid arthritis, juvenile idiopathic arthritis and vitiligo17, 18, 19, while the latter is associated with allergy20. The gene discussed is LPP; the disease is juvenile idiopathic arthritis.