It is a complex transdifferentiation process, orchestrated by several transcription factors (Zeb1/2, Snail1, Snail2 (Slug), Twist 1/2, Goosecoid, FOXM1, FOXC1, and FOXC2 among others) endowing breast tumor cells with enhanced self‐renewal, tumor initiating capacity, invasiveness and resistance to apoptosis 26, 28, 96, 97, 98. Here, SNAI2 is linked to breast neoplasm.