In line with previous results3, comparison of WT and Mut mice reveals that the loss of myeloid cell-derived VEGF results in lower levels of VEGF within the tumours (Fig. 2a for LLC and Supplementary Fig. 1A for B16), as well as in vascular normalization (Fig. 2b–d for LLC and Supplementary Fig. 1B–D for B16), increased pericyte coverage (Fig. 2d for LLC and Supplementary Fig. 1D for B16) and decreased tumour hypoxia (Fig. 2e,f for LLC and Supplementary Fig. 1E for B16). Here, VEGFA is linked to neoplasm.