Ovothiol A, from Paracentrotus lividus oocytes, induced the formation of autophagic vacuoles and expression of specific autophagic molecular markers, LC3B-I, LC3B-I to LC3B-II conversion, and BECN1 in human liver carcinoma Hep-G2 cells [51]. The gene discussed is MAP1LC3B; the disease is hepatocellular carcinoma.