Since TP53 family members could transcriptionally regulate many autophagic genes and often overlap in their function [10,11,12,13,14,15,16], we selected two distinct representative autophagy genes for the specific expression of each TP53 member protein in tested tumor cell lines, such as TP63—for SCC-11 cells, TP73—for U87-MG cells, and TP53—for RKO cells [27,45,46]. This evidence concerns the gene TP53 and neoplasm.