We found that the exposure of tumor cells to selected anticancer marine compounds led to an increased enrichment in the preferential binding of TP53 family transcriptional factors to the selected autophagic gene promoters (Figure 5A) via recognition of the TP53/TP73/TP63 responsive elements found in the specific regions of these gene promoters (Supplementary Figures S1–S6). The gene discussed is TP53; the disease is neoplasm.