Both marine compounds (ILQ and EMQ) were found to stabilize the TP53 protein through a TP53 phosphorylation at the S15 position in HCT116 and RKO colon cancer cells, leading to upregulation of the CDKNA1 expression, thereby suppressing the proliferation of colon cancer cells [43]. The gene discussed is TP53; the disease is malignant colon neoplasm.