CD34 and inherited retinal dystrophy: Our previous work has established that they are capable of integrating into the retinal vasculature in NOD-SCID mice with acute ischemia-reperfusion injury following intravitreal injection, and remain there long term with no ocular and systemic adverse effects.15 In our current study, intravitreal injection of human BM CD34+ cells was well tolerated in eyes with hereditary retinal degeneration with no ocular or systemic adverse effects noted during the course of the study.