Mutations in the transforming growth factor beta-induced (TGFBI) gene are responsible for stromal dystrophies, such as lattice corneal dystrophy (LCD) and granular corneal dystrophy (GCD).[1] Mutations in corneal carbohydrate sulfotransferase 6 (CHST6) gene are responsible for macular corneal dystrophy (MCD).[2] The clinical manifestations vary significantly, depending on the anatomical location, and the pattern and severity of the protein deposition. This evidence concerns the gene TGFBI and macular corneal dystrophy.