KLF8 and ovarian carcinoma: To further investigate the mechanism by which C17orf91 elicited its oncogenic role, we explored whether C17orf91 could regulate key pro-metastatic genes, such as KLF8 [10], MYC [11], SNAI2 [12], TWIST1 [13], ZEB1 [14] and ZEB2 [15] in ovarian cancer.