ITIH4 and HIV infectious disease: Figure 6 showed SWI/SNF protein AT-rich interactive domain-containing protein (ARID1A) expression in HIV-1 gp120 with cocaine (Fig. 6A) and HIV infection with cocaine (Fig. 6B) which were significantly upregulated when compared with control. Figure 6(C,D) shows the densitometry analysis of ARID1A expression in the presence of HIV-1 gp120 protein and HIV infection indicating significant upregulation during cocaine (p < 0.05), HIV-1 gp120 (p < 0.01) and HIV-1 gp120 with cocaine (p < 0.001), and HIV infection (p < 0.01) and cocaine with HIV infection (p < 0.001).