Based on UCSC database (ChIP-Seq) search, we found that YY1 was restricted to the BCCIP transcriptional start site proximal region in different types of cell lines including human lung carcinoma type II epithelium-like A549, human liver hepatocellular carcinoma HepG2 and human colon cancer HCT116. The gene discussed is YY1; the disease is malignant colon neoplasm.