This model included a transcript isoform for the cancer driver TPM1, which is highly included in MITF+ and was linked before to tumor growth [33] (Additional file 2: Figure S5c), as well as for RAB27A, a component of the melanosome that is transcriptionally regulated by MITF [34] and that is lowly included in MITF+ samples (Additional file 2: Figure S5d). Here, RAB27A is linked to cancer.