KMT2A and acute myeloid leukemia: Additional whole-exome sequencing was performed in four MLL-rearranged cases where only a few lesions were identified by targeted resequencing, one normal karyotype AML (UPN 2014-018), and one AML with monosomy 7 (UPN 2014-009) (Supplementary Tables 3,4, Supplementary Data 1).