However, NFL is also increased in other neurological conditions, including inflammatory diseases (Mattsson et al, 2010; Christensen et al, 2013), Creutzfeldt‐Jakob disease (van Eijk et al, 2010), acute neuronal ischemia (Merisson et al, 2016), subcortical vascular dementia (Skillbäck et al, 2014), atypical parkinsonian disorders (Hall et al, 2012), and frontotemporal lobe dementia (FTD) (Petzold et al, 2007; Pijnenburg et al, 2007; Landqvist Waldo et al, 2013) where levels correlate with disease severity (Scherling et al, 2014). This evidence concerns the gene NEFL and frontotemporal dementia.