However, no association between HNF1A, LEPR, GCKR, NLRP3, IL1F10, PPP1R3B, ASCL1, HNF4A and SALL1 and both CRP serum levels at RA diagnosis and at the time of the carotid US study was disclosed (Supplementary Table S3). This evidence concerns the gene NLRP3 and rheumatoid arthritis.