In this regard, the mean ± SD of CRP serum levels at RA diagnosis in patients carrying the minor CRP rs1417938A allele was 12.66 ± 25.32 mg/l versus 9.80 ± 19.39 mg/l in those carrying the major CRP rs1417938T allele (p = 0.0002) (Supplementary Table S1). This evidence concerns the gene CRP and rheumatoid arthritis.