CRP and rheumatoid arthritis: Consistent with these results, the mean ± SD of CRP serum levels at RA diagnosis in patients carrying the ACC haplotype (which harbors the minor CRP rs1417938A allele) was 14.08 ± 28.28 mg/l versus 10.23 ± 19.90 mg/l in those patients carrying the TCC haplotype, the most common haplotype found in our series (p = 0.0002) (Supplementary Table S2).