TACSTD2 was proposed to be a Wnt target [34] identified through consistent gene expression changes in APC-mutant intestinal adenomas from humans and mice; EFNB1 :Eph-related receptor is a Wnt signalling target gene in colorectal cancer [35] that binds to the EFNB1 ligand. This evidence concerns the gene TACSTD2 and colorectal cancer.