Metabolic pathways, calcium signaling pathway, PI3K-Akt signaling pathway, axon guidance, pathways in cancer, MAPK signaling pathway, tight junction, dilated cardiomyopathy, circadian entrainment, proteoglycans in cancer, regulation of actin cytoskeleton, cholinergic synapse and focal adhesion pathways were selected. The gene discussed is AKT1; the disease is cancer.