TF and ciliopathy: Currently, four other ciliopathy associated proteins, OFD1, ODF2, C2CD3 (C2 calcium-dependent domain containing 3) and DZIP1 (DAZ-interacting zinc finger protein 1), have been implicated in TF formation by acting on the outer wall of the mother centriole to promote fibre/appendage assembly24, 28, 48, 49, 50.