In particular, 8 genes (Mx1, EPSTI1, XAF1, IFI44L, GBP1, SAMD9, SAMD9L, and CMPK2) were expressed in the highly resistant cell lines HPAF-II and Hs766T but not the highly permissive cell lines MIA PaCa-2 and Capan-1 in the absence of virus infection. The gene discussed is MX1; the disease is viral infectious disease.