AKT3 and neoplasm: Akt1 KD had the highest (p<0.05), while Akt2 KD had the lowest (p<0.05) incidence of tumor cell apoptosis (Figure 3b), while Akt3 KD tumors had less apoptosis than Akt1 KD tumors, but more than Akt2 KD (Figure 3b).