Importantly, results from IHC (Fig 3F) and IF (S3E Fig) experiments suggested that while H37Rv- and BCG-induced granulomas from wild-type mice express elevated levels of JMJD3, ADRP and CD36, expression of these genes in granulomas from tlr2-null mice was significantly abrogated. The gene discussed is TLR2; the disease is Granuloma.