The ratios of CD19+CD40+, CD19+CD80+, and CD19+CD11b+ B cells were positivelycorrelated with the PASI scores of psoriasis vulgaris at the active stage,arthropathic psoriasis, and pustular psoriasis (r=0.452, r=0.712, r=0.320, andP=0.0037, P=0.0025, and P=0.0044, respectively).The ratios of CD19+CD44+, CD19+CD86+, and CD19+HLA-DR+ B cells were also positivelycorrelated with the PASI scores of psoriasis vulgaris at the active stage (r=0.640,r=0.914, r=0.334, and P=0.0029, P=0.0011 andP=0.0043, respectively). The gene discussed is CD44; the disease is pustular psoriasis.