An 81-year-old man with past medical history including atrial fibrillation, coronary artery disease s/p myocardial infarction and ventricular tachycardia/ventricular fibrillation s/p automatic implantable cardioverter-defibrillator placement was diagnosed with metastatic BRAF wild-type melanoma. Here, BRAF is linked to myocardial infarction.