IL10 and colitis: One study demonstrated that continual (25 weeks) prophylactic dietary supplemention with Aquamin, a mineral extract obtained from red algae Lithothamnion corallioides, ameliorated the serverity of spontaneous colitis in IL-10−/− mice on C57BL/6J background, but had no affect on IL-10−/− mice on a BALB/c background (607).