Other agents that have been used to lower tumor IFP include bevacizumab, tumor necrosis factor-alpha, dexamethasone, prostaglandin E1-methyl ester, labradimil, docetaxel, nicotinamide, etc. [3, 10] However, all of these agents have some limitations, including toxicity to normal tissue or lack of tumor selectivity. The gene discussed is TNF; the disease is neoplasm.