AFP and neoplasm: Besides fulfillment of the particular selection criteria, significant differences between these subgroups were found with respect to AFP concentration (p < 0.001), number of tumors (p < 0.001), size of the largest tumor (p < 0.001), total tumor volume (p < 0.001), microvascular invasion (p < 0.001), tumor differentiation (p = 0.037), and neoadjuvant treatment (p = 0.040).