This miR has been associated with obesity, and a candidate study of miR-519d-3p in placenta by Ding et al. [115] suggested that by directly targeting the 3‘UTR of matrix metalloproteinase-2 (MMP-2), one of many extracellular matrix proteases, miR-519d-3p was able to suppress trophoblast invasion and migration [121]. Here, MMP2 is linked to obesity disorder.