Of these parameters, CRP (p = 0.014), creatinine (p = 0.026), and body weight (p = 0.015) were significantly associated with Skin AF over time, whereas SOFA (p = 0.113), PaO2/FiO2 ratio (p = 0.91), and norepinephrine dose (p = 0.77) were not. This evidence concerns the gene CRP and atrial fibrillation.