Besides, the combination of Kruppel-like factor 4 (KLF4) overexpression and curcumin had significant anti-proliferation, pro-apoptosis and anti-invasion effects on human gastric carcinoma cells, indicating that KLF4 was a potential therapeutic target, and curcumin was a promising therapeutic drug in stomach cancer [62]. Here, KLF4 is linked to gastric carcinoma.