However, no difference in BDCA3+ DC numbers could be detected between patients with high or low fibrosis or liver damage, as measured by alanine transaminase (ALT) (Fig 1D), suggesting that mostly active viral replication, and possibly consecutive local production of inflammatory cytokines/chemokines, rather than liver damage induces infiltration of BDCA3+ DCs into the liver. The gene discussed is GPT; the disease is fibrosis.