CD8A and tonsillar squamous cell carcinoma: Nasman et al. found a significantly higher number of CD8+ tumor infiltrating lymphocytes and Foxp3+ Tregs in HPV-positive tonsillar SCC patients as compared with HPV-negative patients, and higher level of CD8+ T-cell infiltration and a high local CD8+ /Treg ratio were associated with better clinical outcome in tonsillar SCC cases [92].