As seen in Figure 1D, the expression of cytokines known to be increasingly expressed at H. pylori-infected gastritis including Vascular endothelial growth factor (VEGF), Cyclooxygenase (Cox)-2, IL-1β, IL-8, INF-γ, and IL-6, [21], were all significantly increased in H. pylori-infected WT compared to non-infected vehicle control group (P < 0.001). This evidence concerns the gene IL6 and gastritis.