Expression of CXCR4 increased in all Ewing sarcoma cell lines following exposure to GSK-126 (Figure 5E) and this was accompanied by loss of the H3K27me3 modification (Figure 5F) but no change in H3K4me3 enrichment at the CXCR4 promoter (Figure 5G). The gene discussed is CXCR4; the disease is Ewing sarcoma.