CAVIN1 and muscular dystrophy: Moreover, a lipodystrophic phenotype was observed in PTRF null mice (Ding et al., 2014; Liu et al., 2008) that is similar or identical to that of human patients with inactivating PTRF mutations who also display a type of muscular dystrophy (Ardissone et al., 2013; Dwianingsih et al., 2010; Hayashi et al., 2009; Jelani et al., 2015; Shastry et al., 2010).