In our study, FLT3-ITD and NPM1 mutations were considered in the risk stratification according to NCCN Guidelines (Version 1.2015 Acute Myeloid Leukemia), we included risk stratification but not mutational status of FLT3-ITD and NPM1 as individual variables in our multivariate analysis. This evidence concerns the gene FLT3 and acute myeloid leukemia.