ESR1 and neoplasm: In terms of miRNAs exhibiting higher expression in TamRs vs. MCF-7/S0.5 cells, TamR1 and TamR4 shared 22 miRNAs; TamR1 and TamR8 shared 21 miRNAs, including the tumor suppressors miR-181b, oncomiR miR-210 and a known ER regulator miR-18a [18]; and finally, TamR4 and TamR8 shared 20 upregulated miRNAs, including oncomiRs miR-210, miR-203, miR-18a* (Figure 1A and Supplementary Table 1).