In the current study, to evaluate the therapeutic effect of local administration, using ovalbumin (OVA) as an experimental allergen, asthma model mice were treated intratracheally with a fixed ratio of IL-2 and dexamethasone as reported before (50,000 IU IL-2: 12.5 μg dexamethasone versus 400,000 IU IL-2: 100 μg dexamethasone)11. This evidence concerns the gene IL2 and asthma.