While it was displayed reduced IGF-1 in Non-PSD group (FBonferroni = −26.98, SE = 9.71, P = 0.037, 95%CI, −52.93~-1.02) and elevated IGF-1R in PSD of protein (post hoc nonparametric test, P < 0.05) aspect related to MDD patients (see Table 3). The gene discussed is IGF1; the disease is major depressive disorder.