HIF1A and non-small cell lung carcinoma: For example, lncRNA-XIST, a product of the X-inactive specific tran­script gene, and lncRNA HIF 1 alpha-antisense RNA 1 (HIF1a-AS1) are up-regulated in non-small cell lung cancer (NSCLC), and can be used as a diagnostic biomarker for NSCLC screening [15].