Wu et al. [35] reported that the AUC of a 5-lncRNA signature, including lncRNA-LET, PVT1, PANDAR, PTENP1 and linc00963 was higher than that of one lncRNA after they detected serum samples from 71 ccRCC patients, 62 healthy controls, and 8 patients with benign renal tumors. The gene discussed is PVT1; the disease is nonpapillary renal cell carcinoma.