ST8SIA4 and chronic myelogenous leukemia, BCR-ABL1 positive: Furthermore, analysis of miR-181c and ST8SIA4 expression in CML patients by Spearman's correlation analysis showed a significant inverse correlation (r= −0.7355, P =0.000; Figure 4C) Taken together, the results indicated that miR-181c targets ST8SIA4 to repress its expression by binding to 3′-UTR regions.