Their cumulative model was constructed from polymorphism p.Lys751Gln (rs13181) in ERCC2 and p.Val16Ala in antioxidant enzyme gene SOD2. The patients with one or two low-risk genotypes had improved recurrence-free survival (RFS), breast cancer specific survival (BCSS) and overall survival (OS). Here, ERCC2 is linked to breast cancer.