ACTA2 and Hepatic fibrosis: Notably, among the top Canonical Pathways, the first top-ranked was Hepatic Fibrosis/Hepatic Stellate Cell Activation based on such molecules as COL1A1, IGFBP4, CCR5, FN1, CTGF, TIMP1, ACTA2, IL10RA, CCL5, FAS, EGFR.