HTN1 and dental caries: Western blotting was performed in parallel with constant conditions, and we found that the levels of salivary histatin-1 were higher in children with s-ECC after treatment for 4 weeks compared with before treatment (P < 0.01), which was consistent with the tendency of expression of the two peptides with experimental m/z values of 1723.7 and 1886.5 during different period of treatment of dental caries in MALDI-TOF MS.